References
*These guidelines on reducing the risk of surgical site infections are general to triclosan-coated sutures and are not specic to any one brand.
† 2021 NICE MedTech guidelines recommend the use of Ethicon Plus Antibacterial Sutures as part of a bundle of care for preventing surgical site infection.33
¶ In a meta-analysis that included 21 RCTs, 6462 patients, 95% CI: (14, 40%), P<0.001.
#All triclosan-coated sutures in these RCTs were Ethicon Plus Antibacterial Sutures (MONOCRYL™ Plus Antibacterial [poliglecaprone 25] Suture, Coated VICRYL™ Plus Antibacterial [polyglactin 910] Suture, and PDS™ Plus Antibacterial [polydioxanone] Suture).
**Meta-analysis only included traditional (non-barbed) sutures.
1. Ethicon Wound Closure Manual 2012. Ethicon, Inc.
2. Berrios-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152(8):784-791.
3. Ban KA, Minei JP, Laronga C, et al. American college of surgeons and surgical infection society: surgical site infection guidelines, 2016 update. J Am Coll Surg. 2017; 224(1):59-74.
4. Nonnenmann H. Time Zero Tissue Holding – Competitive Claims Comparisons for STRATAFIX Knotless Tissue Control Devices vs Various Products (100326296). 2015. Ethicon, Inc
5. STRATAFIX™ Symmetric PDS™ Plus Knotless Tissue Control Device Instructions for Use. Ethicon, Inc.
6. V-Loc™ 180 Absorbable Wound Closure Device Instructions for Use. Medtronic.
7. Ming X, Rothenburger S, Nichols MM. In vivo and in vitro antibacterial efficacy of PDS Plus (polidioxanone with triclosan) suture. Surg Infect (Larchmt). 2008;9(4):451-457.
8. Berríos-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017. JAMA Surg. doi:10.1001/jamasurg.2017.0904.
9. Global guidelines on the prevention of surgical site infection. World Health Organization website. http://www.who.int/gpsc/ssi-prevention-guidelines/en/. Accessed October 5, 2018.
10. Ban KA, Minei JP, Laronga C, et al. American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update. J Am Coll Surg. 2016;224:59-74.
11. National Institute for Health and Care Excellence (NICE) Guideline. Surgical site infections: prevention and treatment. NICE website. https://www.nice.org.uk/guidance/ng125/chapter/Recommendations#closuremethods. Accessed February 14, 2022.
12. Prevention of postoperative wound infections. Recommendation of the Committee for Hospital Hygiene and Infection Prevention (KRINKO) at the Robert Koch Institute. Bundesgesundheitsbl. 2018; 61(4):448-473.
13. De Jonge SW, Atema JJ, Solomkin JS, Boermeester MA. Meta-analysis andtrial sequential analysis of triclosan-coated sutures for the prevention of surgical-site infection. Br J Surg. 2017;104(2):e118-e133.
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